�Researchers linear cancer trials are a great deal critical of the Research Ethics Committee (REC) work they have to go through to get their trials sanctioned, complaining that it's excessively complex, onerous and sometimes unreasonable. In the UK only 17% of research study applications are apt immediate favorable opinion by RECs.
But a new study from the University of Leicester, recently reported in The Lancet Oncology, suggests that RECs english hawthorn sometimes identify important problems in applications to conduct cancer trials.
The Leicester study, funded by the National Research Ethics Service, looked at 80 anonymised NHS REC decision letters concerning cancer the Crab trials, written between March 2004 and December 2006.
When reviewing applications to conduct cancer trials, the issue RECs are most likely to raise is that of informed consent. Committees are often concerned that the information that researchers propose to give patients may not be in linguistic process that can be easily understood. They also monish researchers from presenting trials too enthusiastically, and seek to prevent researchers from providing shoddy information. One Committee pointed out that the genus Cancer drug side-effects were described as mild on the patient info sheet, just in the investigator's leaflet it was noted that several patients had experienced serious adverse events sentiment to be related to the drug.
The study found that RECs identify a high rate of mistakes in applications, including missing info, ticking the wrong boxes, errors in the info provided and not following correct procedures.
The findings support the conclusion that RECs, though by their constitution slightly bureaucratic, leave an significant independent check on clinical trials by ensuring that investigators do not miss important information or undervalue risks in the information they give patients.
Professor Mary Dixon-Woods, of Medical Sociology in the Department of Health Sciences at the University, commented: "There have been a destiny of complaints about REC procedures from researchers in recent years. They often find the process onerous and bureaucratic. However, this study is the offset time anyone has consistently analysed what RECs are saying approximately cancer trial proposals.
"RECs are looking at for evidence that researchers are sensitive to ethical issues, in particular to participants' interests, and that information disposed to potential participants explains the trial fully and truthfully. Researchers can amend their chances of success at ethical review by really secure preparation."
The study, led by Professor Dixon-Woods, was carried out with Emma Angell, Carolyn Tarrant and Anne Thomas, in the Social Science Research Group in the Department of Health Sciences at the University of Leicester and the Department of Cancer Studies and Molecular Medicine at the Leicester Royal Infirmary.
University of Leicester
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Wednesday, 3 September 2008
Sunday, 24 August 2008
Matt Damon - Bourne Star Matt Damon Becomes Father For Second Time
Matt Damon's wife Luciana has minded birth to the couple's second daughter, it has been revealed.
Gia Zavala Damon was natural on Wednesday, the actor's representative Jennifer Allen told People magazine.
She joins older sisters Isabella, 2, and ten-year-old Alexia (from Luciana's previous marriage ceremony) in the Damon household.
"Everyone's doing capital," Allen added. "She is a levelheaded baby girl."
According to Damon's Ocean's Eleven co-star George Clooney, the 37-year-old is a "phenomenal" father.
"He absolutely adores those kids. He's doing it truly well," he told People magazine.
After complementary reshoots on upcoming military thriller Green Zone, the Bourne Ultimatum star is to conduct the rest of the year cancelled to spend time with his family, he has confirmed.
On the same day on which Damon's family grew, it was revealed that his Good Will Hunting co-writer and co-star Ben Affleck has a second girl on the way.
Affleck's actress wife Jennifer Garner confirmed after months of hypothesis that she is expecting another daughter.
"We're so excited, obviously," the Alias lead told Access Hollywood at Walt Disney's tenth Anniversary party for the Baby Einstein line of product.
"It always makes me laugh when people sound out 'Is she?' 'Isn't she [meaning]?' It's like eventually you will know, so just chill out for a moment," she joked.
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Wednesday, 6 August 2008
Miley Cyrus Rival Adam Sevani Predicts Winner Of M&M Cru/ ACDC Dance-Off
Miley Cyrus mania will hit a fever pitch when she hosts the Teen Choice Awards on Sunday in Los Angeles. And when she does, she'll consume a small help from her YouTube dance rival and "Step Up 2: The Streets" star Adam Sevani. In fact, the winner of the on-going dance-off between Miley and Mandy Jiroux's M&M Cru and Sevani and Jon M. Chu's ACDC will be declared at the show.
While the 16-year-old Sevani didn't reveal too many details about the usher, which pose Monday, he did make a prognostication when MTV News caught up with him at rehearsals.
"I think they're gonna win," he confessed. "Just for personal reasons, and, you know, because it's Miley and they're gonna do dear. We're gonna do sound too. The audience is gonna voter turnout, so we'll see."
Sevani promised that he has "a bunch of exciting styles of dance" for his routine, only he has yet to see what Cyrus will break prohibited with. "No, I haven't seen it � that's the playfulness part!" he said. "We're not gonna see it until it's live, so I have no idea."
Of course, Cyrus and Sevani have become YouTube sensations with their battles for dance mastery, which have even lED celebrities like Chris Brown, Adam Sandler and Ryan Seacrest to get mired. Eventually, it was decided that the only way to settle the score was by taking it to a bigger stage, like the Teen Choice Awards.
"Yeah, I was surprised it got so self-aggrandizing that we had to do it somewhere like this," Sevani said. "Finally, it's here!"
Sevani is no stranger to performing at the Teen Choice Awards: He was Kevin Federline's backup dancer when Brit's ex performed on the show in 2006. He said he's filled with excitement for this year's show. "It's all building up," he said. "The tension is building up and hoi polloi are acquiring nervous. We're gonna smoke [the audience]!"
Although he dodged Cyrus-related questions like a pro, Sevani did suppose that she is very humble, even though she's one of the biggest pop stars in the world. "Of course she is," he said, "What do you expect? I mean, we're real people. I accept nothing bad to say about anybody."
Sevani has no date for the night, but seemed intrigued by the idea that possibly, just maybe, Cyrus might show up on his arm. "We'll see," he laughed. "We'll see."
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Friday, 27 June 2008
Diamond Neil
Artist: Diamond Neil
Genre(s):
Rock
Discography:
Tap Root Manuscript
Year: 1972
Tracks: 12
The Ultimate Collection CD1
Year:
Tracks: 19
The Essential Collection
Year:
Tracks: 16
Jonathan Livingston Seagull
Year:
Tracks: 12
In my Lifetime (1 of 3)
Year:
Tracks: 27
Hot August Night
Year:
Tracks: 1
Greatest Hits 1966 To 1992 CD1
Year:
Tracks: 19
19XX - Greatest Hits Live!
Year:
Tracks: 17
Thursday, 19 June 2008
Madonna - Madonna Enlists Tyson For Malawi Campaign
Pop superstar MADONNA has enlisted the support of former boxing champion MIKE TYSON in her campaign to help the impoverished nation of Malawi.
The Holiday hitmaker has become emotionally attached to the country after adopting tot David Banda from an orphanage there in 2006.
And the star is keen to help raise money to improve standards of living there and heighten awareness of diseases including AIDS.
Madonna has now reportedly approached Tyson to help spearhead her Raising Malawi charity effort after the pair met at the Cannes International Film Festival earlier this week (begs19May08).
A source tells British newspaper the Daily Mirror, "Madonna thinks Mike is amazing and he has promised to fly with her to Malawi in late summer to promote awareness of children with AIDS there.
"Mike is eager to show he's turned over a new leaf and thinks this is the perfect way to do it."
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Wednesday, 11 June 2008
Busted - Willis Enters Rehab
Former BUSTED star MATT WILLIS is seeking help for his addiction to drugs and alcohol a month before his wedding.
Willis entered The Priory rehab clinic in London on Thursday (05Jun08) after paparazzi shots of him visibly drunk with troubled star Amy Winehouse appeared in the British tabloid newspapers.
His fiancee, U.K. TV presenter Emma Griffiths, has reportedly ordered he seek help for his addictions ahead of their nuptials next month (July08).
A source tells British newspaper the Mirror, "He went too far after a night out with Amy. He was so out of it he started swinging at photographers.
"He and Emma are supposed to be getting married...but she has told him he needs to sort himself out before she becomes his wife."
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Thursday, 5 June 2008
Lily Allen to play lady-loving vampire
London (ANI): English singer songwriter Lily Allen has signed up for a cameo role in Mathew Horne and James Corden's big-screen debut Lesbian Vampire Killers. It was after a lot of cajoling from the two, who had appeared on her TV chat show, that Allen agreed to play a naughty lady-loving vampire in the movie, which is out next year. "James wants Lily to take on a bigger part but she is happy with a cameo," the Sun quoted a source as saying. Meanwhile, even though Allen is great friends with Horne and Corden, she has not been able to impress The Kooks front man Luke Pritchard, who is still immune to her charms. The Smile singer had badmouthed him on her MySpace page last year, but she is now trying to get back in his good books by covering the band's hit Na�ve. But Pritchard, who had been friends with Allen at school when they were 13-years-old, is not falling for any of it.
Tuesday, 3 June 2008
'Prince Caspian' set for boxoffice crown
'Narnia' sequel could gross $85 mil with limp competition
Disney has nabbed one heck of a nice release slot this weekend.
For starters, last session's disappointing "Speed Racer" bow means Disney's all-important opener "The Chronicles of Narnia: Prince Caspian" will see only limp competition from the rival family film. Then, though the following weekend features the debut of presumed boxoffice behemoth "Indiana Jones and the Kingdom of the Crystal Skull," it's the four-day Memorial Day session, and that should offer plenty of moviegoing interest for both releases.
There's already talk that the "Narnia" sequel will gross north of $300 million during its domestic run, as first installment "The Lion, the Witch and the Wardrobe" rung up $292 million and sequels tend to do better. As for how big "Prince" will open, it likely will be measured against two precedents: the $65.6 million bow of its franchise progenitor in December 2005 and the $121.6 million debut of DreamWorks Animation's "Shrek the Third" during the comparable frame in May 2007.
Industry consensus has "Prince" opening maybe 40% higher than the original and grossing $85 million or more this weekend. Yet the year-ago "Shrek" figure is well out of reach, so the weekend boxoffice probably will underperform the comparable 2007 frame despite another lucrative session -- just as with the huge opening for "Iron Man" two weeks ago.
The PG-rated "Prince" has been scoring high in prerelease surveys for must-see sentiment among all demographics and has drawn solid early reviews from critics. The second book in a 1950s children's literature series written by the theologically rooted C.S. Lewis, the sequel features a more adult central character via the title role, played by Ben Barnes ("Stardust").
"This is the quintessential general-audience film -- moms and dads, families, date-pic couples, teens by themselves -- this plays to everybody," Disney distribution president Chuck Viane said.
The film will play in slightly more than 3,900 theaters during its first weekend. Disney executives said they didn't feel a need to push for 4,000 playdates, are in every location they want to be and weren't handicapped by the previous 4,000-plus bow of "Iron Man" or the looming market entry of the "Indiana Jones" sequel.
Walden Media is a co-financer and equity partner on the film, which totes production costs of nearly $200 million.
Elsewhere this weekend, Warner Bros. hopes "Speed Racer" can mount a decent second-week showing. But the likelihood is its grosses will plunge with the market entry of "Prince," yielding another downbeat session for the distributor and its partner Village Roadshow.
On the other hand, Paramount and Marvel hope that repeat viewings and continued broad interest in "Iron Man" will carry the PG-13 film to another solid weekend. The May opener almost no one thought could get to $300 million suddenly is a candidate to do just that, but it will bear watching how the comic book adaptation performs this weekend and next.
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Runes Order
Artist: Runes Order
Genre(s):
New Age
Ambient
Other
Discography:
The Hopeless Days
Year: 2004
Tracks: 15
The Dark Side Of Brain
Year: 2002
Tracks: 1
The Art Of Scare And Sorrow
Year: 2002
Tracks: 14
Il Sonno del Sogno
Year: 2001
Tracks: 8
Black Odal Symphony
Year: 2000
Tracks: 10
The Will Of The Runes Live 1994,1997, 1998
Year: 1998
Tracks: 7
1988-2022
Year: 1998
Tracks: 9
Waiting Forever Memories Remain
Year: 1997
Tracks: 14
The Land Of Silence
Year: 1995
Tracks: 10
Room 39
Year: 1995
Tracks: 5
Winter
Year: 1994
Tracks: 8
Quadridimensional Noisescapes
Year: 1994
Tracks: 4
No Future
Year: 1993
Tracks: 10
Electronic Winter Landscape (tape)
Year: 1993
Tracks: 12
Tears In The Snow
Year: 1991
Tracks: 13
Odisseum
Year:
Tracks: 10
Ike Turner died from cocaine overdose
Soul singer Ike Turner died from a cocaine overdose, according to the San Diego County medical examiner.
The 76-year-old was found dead at his home near San Diego on 12 December last year.
The medical examiner yesterday said that an autopsy proved that a long history of cardiovascular disease and emphysema had contributed to the star's death.
Turner reportedly had a history of cocaine addiction stretching over 30 years.
The 76-year-old was found dead at his home near San Diego on 12 December last year.
The medical examiner yesterday said that an autopsy proved that a long history of cardiovascular disease and emphysema had contributed to the star's death.
Turner reportedly had a history of cocaine addiction stretching over 30 years.
Sergey Lukin
Artist: Sergey Lukin
Genre(s):
Other
Discography:
Transcriptions and Arrangements For Domra
Year: 2003
Tracks: 10
Culture and Don Carlos
Donald Byrd
Artist: Donald Byrd
Genre(s):
Jazz
funk
Jazz: Funk
Blues
Discography:
Blackjack
Year: 2004
Tracks: 7
Byrd in Hand
Year: 2003
Tracks: 6
Street Lady
Year: 1999
Tracks: 6
A New Perspective
Year: 1999
Tracks: 5
Blue Breakbeats
Year: 1998
Tracks: 7
Electric Byrd
Year: 1996
Tracks: 4
His Majesty King Funk: Up with Donald Byrd
Year: 1995
Tracks: 14
A City Called Heaven
Year: 1994
Tracks: 8
Black Byrd
Year: 1992
Tracks: 7
Harlem Blues
Year: 1987
Tracks: 7
Thank You ... For F.U.M.L (Funking Up My Life)
Year: 1978
Tracks: 8
Ethiopian Knights
Year: 1971
Tracks: 3
Kofi
Year: 1970
Tracks: 5
Fancy Free
Year: 1969
Tracks: 4
Slow Drag
Year: 1967
Tracks: 6
Creeper
Year: 1967
Tracks: 7
Mustang!
Year: 1966
Tracks: 8
Groovin' for Nat
Year: 1962
Tracks: 11
Royal Flush
Year: 1961
Tracks: 6
Chant
Year: 1961
Tracks: 6
![Fuego [The RVG Edition 2005]](http://img.mp3fiesta.com/covers/21/21317/alb_87889_th.jpg)
Fuego [The RVG Edition 2005]
Year: 1960
Tracks: 6
Byrd in Flight
Year: 1960
Tracks: 6
At the Half Note Cafe Vol.1
Year: 1960
Tracks: 8
At The Half Note Cafe Vol. 2
Year: 1960
Tracks: 6
Winterset
Year: 1958
Tracks: 9
Off to the Races
Year: 1958
Tracks: 6
Jazz in Paris: Donald Byrd Quintet Parisian Thoroughfare
Year: 1958
Tracks: 8
Jazz in Paris: Byrd in Paris
Year: 1958
Tracks: 5
Two Trumpets
Year: 1956
Tracks: 5
Donald Byrd was considered unrivaled of the finest hard federal Bureau of Prisons trumpeters of the post-Clifford Brown earned run average. He recorded prolifically as both a leader and sideman from the mid-'50s into the mid-'60s, most a great deal for Blue Note, where he established a reputation as a self-coloured stylist with a clean tone of voice, clear articulation, and a hang for melodicism. Toward the end of the '60s, Byrd became spell-bound with Miles Davis' move into fusion, and started recording his have forays into the field. In the early '70s, with the help of brothers Larry and Fonce Mizell, Byrd perfected a bright, breezy, commercially potent take on nuclear fusion that was discrete from Davis, incorporating tighter arrangements and more of a smooth soul influence. Opinions on this phase of Byrd's career diverge wildly -- jazz purists absolutely scorned it, stigmatisation Byrd a sellout and the records a betrayal of endowment, just enraptured jazz-funk fans regard it as some of the about innovative, long-suffering play of its kind. In fact, proportionally speaking, Byrd is held in regular higher admiration by that audience than by straight-ahead jazz fans wHO love his hard bebop yield.Donaldson Toussaint L'Ouverture Byrd II was born in Detroit, MI, on December 9, 1932. His padre, a Methodist diplomatic minister, was an amateur instrumentalist, and Byrd was already an accomplished trumpeter by the time he finished high schooling, having performed with Lionel Hampton. Byrd served a stint in the Air Force, during which time he played in a military stripe, and after completed his bachelor's degree in music at Wayne State University in 1954. He touched to New York in 1955 to get his master's at the Manhattan School of Music, and before long began acting with pianist George Wallington's grouping. In December of that year, he was invited to link up Art Blakey's Jazz Messengers, fill a chair formerly held by his perfection, Clifford Brown, and Kenny Dorham. Byrd as well began his recording calling during this period, in the lead respective sessions (by and large for Savoy) and working often as a sideman, peculiarly at the Prestige judge. He left hand the Jazz Messengers in 1956 and united up with Max Roach; he went on to flirt with the likes of John Coltrane, Sonny Rollins, and Red Garland, and as well co-founded the Jazz Lab Quintet with altoist Gigi Gryce in 1957.In 1958, Byrd signed an exclusive recording get with Blue Note, and as well formed a band with baritonist Pepper Adams, wHO would stay Byrd's regular collaborator until 1961. Byrd's Blue Note debut was 1958's Off to the Races, and he and Adams collaborated on a series of excellent hard bebop dates over the adjacent three days, including William Byrd in Hand (1959), At the Half Note Cafe, Vols. dozen (1960), The Cat Walk (1961), and Royal Flush (as well 1961), among others. Another 1961 recording, Liberate Form, launch Byrd gift a young Herbie Hancock some of his earlier exposure. Following this burst of activeness, Byrd took a sabbatic to continue his studies in Europe, where he spent some metre under the tutelage of the legendary French music pedagog Nadia Boulanger. He returned to the U.S. in 1963 and recorded A New Perspective, a now-classic set that skint new undercoat by incorporating gospel choirs into its arrangements; its signature piece, "Cristo Redentor," became quite an popular.In the mid-'60s, Byrd focussed more of his energies on didactics, and worked diligently to make jazz and its history a legitimate piece of the college syllabus. He taught at Rutgers, Hampton, New York University, and Howard in the tardy '60s, and the final peerless remained a stiff association for much of the '70s. In the lag, Byrd continued to criminal record from time to time, slip a final spate of voiceless bop albums over 1966-1967 that included Mustang! and Cosh. Byrd as well began to study African music, inspired partly by the emerging black-consciousness trend, and became interested in Miles Davis' efforts to court a younger audience (including Byrd's possess students) by experimenting with electronics and funk rhythms. 1969's Fancy Free launch Byrd using electric pianoforte for the first time, with a spaced-out sound that recalled Davis' In a Silent Way. 1970's Electrical Byrd had more than of a Bitches Brew smell, and the jams on 1971's Ethiopian Knights were yearner, funkier, and more aggressive. Byrd truly came into his possess as a fusion creative person when he hooklike up with brothers Larry and Fonce Mizell, wHO began to do by yield, piece of writing, and some musical support duties. Their number one quislingism was 1972's Black Byrd, an eudaimonia, funky blend of nothingness and R&B. Jazz critics scorned the album and called Byrd all sorts of name calling, simply the record was a smash strike; it became the biggest trafficker in Blue Note history, and just lost hit number one on the R&B albums chart. In the awaken of its success, Byrd formed a load-bearing group, the Blackbyrds, world Health Organization were culled from the cream of his music students at Howard University and recorded through the rest of the '70s. Byrd went on to liberation a drawing string of successful LPs in partnership with the Mizell Brothers, including the complex number blaxploitation soundtrack Street Lady (1974), Stepping into Tomorrow (1975), the much-lauded Places and Spaces (1976), and Caricatures (1977). All made the Top Ten on the R&B album charts, and the Places and Spaces single "Change (Makes You Wanna Hustle)" even got significant play in discotheques. Jazz-funk fans revers this period in worldwide, but unremarkably military reserve their highest praise for Street Lady and, specially, Places and Spaces. As a side musical note to his melodious career, Byrd finished law school in 1976, and went on to teach at North Carolina Central University.Following Caricatures, Byrd parted shipway with Blue Note and the Mizell Brothers and moved to Elektra. He recorded several albums over 1978-1983, but regular the most commercially successful, 1978's Thank You...for F.U.M.L. (Funking up My Life), didn't equalise the infectiousness of his Blue Note jazz-funk outings. In 1982, Byrd received his Ph.D. from Columbia Teachers College. He washed-out a few days in the mid-'80s away from transcription, due in role to ill health, but continued to teach, moving on to North Texas State and Delaware State. In the belated '80s and early '90s, Byrd returned to the hard bop of his early days on various roger Huntington Sessions for the Landmark label. He participated in knocker Guru's Jazzmatazz jut in 1993, and with the second Coming of the jazz-rap motion and England's acidic jazz revival, his '70s albums became hugely popular sources for samples. In the interim, Byrd continued his activities as a jazz educator.
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