�Researchers linear cancer trials are a great deal critical of the Research Ethics Committee (REC) work they have to go through to get their trials sanctioned, complaining that it's excessively complex, onerous and sometimes unreasonable. In the UK only 17% of research study applications are apt immediate favorable opinion by RECs.
But a new study from the University of Leicester, recently reported in The Lancet Oncology, suggests that RECs english hawthorn sometimes identify important problems in applications to conduct cancer trials.
The Leicester study, funded by the National Research Ethics Service, looked at 80 anonymised NHS REC decision letters concerning cancer the Crab trials, written between March 2004 and December 2006.
When reviewing applications to conduct cancer trials, the issue RECs are most likely to raise is that of informed consent. Committees are often concerned that the information that researchers propose to give patients may not be in linguistic process that can be easily understood. They also monish researchers from presenting trials too enthusiastically, and seek to prevent researchers from providing shoddy information. One Committee pointed out that the genus Cancer drug side-effects were described as mild on the patient info sheet, just in the investigator's leaflet it was noted that several patients had experienced serious adverse events sentiment to be related to the drug.
The study found that RECs identify a high rate of mistakes in applications, including missing info, ticking the wrong boxes, errors in the info provided and not following correct procedures.
The findings support the conclusion that RECs, though by their constitution slightly bureaucratic, leave an significant independent check on clinical trials by ensuring that investigators do not miss important information or undervalue risks in the information they give patients.
Professor Mary Dixon-Woods, of Medical Sociology in the Department of Health Sciences at the University, commented: "There have been a destiny of complaints about REC procedures from researchers in recent years. They often find the process onerous and bureaucratic. However, this study is the offset time anyone has consistently analysed what RECs are saying approximately cancer trial proposals.
"RECs are looking at for evidence that researchers are sensitive to ethical issues, in particular to participants' interests, and that information disposed to potential participants explains the trial fully and truthfully. Researchers can amend their chances of success at ethical review by really secure preparation."
The study, led by Professor Dixon-Woods, was carried out with Emma Angell, Carolyn Tarrant and Anne Thomas, in the Social Science Research Group in the Department of Health Sciences at the University of Leicester and the Department of Cancer Studies and Molecular Medicine at the Leicester Royal Infirmary.
University of Leicester
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Wednesday 3 September 2008
Sunday 24 August 2008
Matt Damon - Bourne Star Matt Damon Becomes Father For Second Time
Matt Damon's wife Luciana has minded birth to the couple's second daughter, it has been revealed.
Gia Zavala Damon was natural on Wednesday, the actor's representative Jennifer Allen told People magazine.
She joins older sisters Isabella, 2, and ten-year-old Alexia (from Luciana's previous marriage ceremony) in the Damon household.
"Everyone's doing capital," Allen added. "She is a levelheaded baby girl."
According to Damon's Ocean's Eleven co-star George Clooney, the 37-year-old is a "phenomenal" father.
"He absolutely adores those kids. He's doing it truly well," he told People magazine.
After complementary reshoots on upcoming military thriller Green Zone, the Bourne Ultimatum star is to conduct the rest of the year cancelled to spend time with his family, he has confirmed.
On the same day on which Damon's family grew, it was revealed that his Good Will Hunting co-writer and co-star Ben Affleck has a second girl on the way.
Affleck's actress wife Jennifer Garner confirmed after months of hypothesis that she is expecting another daughter.
"We're so excited, obviously," the Alias lead told Access Hollywood at Walt Disney's tenth Anniversary party for the Baby Einstein line of product.
"It always makes me laugh when people sound out 'Is she?' 'Isn't she [meaning]?' It's like eventually you will know, so just chill out for a moment," she joked.
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Wednesday 6 August 2008
Miley Cyrus Rival Adam Sevani Predicts Winner Of M&M Cru/ ACDC Dance-Off
Miley Cyrus mania will hit a fever pitch when she hosts the Teen Choice Awards on Sunday in Los Angeles. And when she does, she'll consume a small help from her YouTube dance rival and "Step Up 2: The Streets" star Adam Sevani. In fact, the winner of the on-going dance-off between Miley and Mandy Jiroux's M&M Cru and Sevani and Jon M. Chu's ACDC will be declared at the show.
While the 16-year-old Sevani didn't reveal too many details about the usher, which pose Monday, he did make a prognostication when MTV News caught up with him at rehearsals.
"I think they're gonna win," he confessed. "Just for personal reasons, and, you know, because it's Miley and they're gonna do dear. We're gonna do sound too. The audience is gonna voter turnout, so we'll see."
Sevani promised that he has "a bunch of exciting styles of dance" for his routine, only he has yet to see what Cyrus will break prohibited with. "No, I haven't seen it � that's the playfulness part!" he said. "We're not gonna see it until it's live, so I have no idea."
Of course, Cyrus and Sevani have become YouTube sensations with their battles for dance mastery, which have even lED celebrities like Chris Brown, Adam Sandler and Ryan Seacrest to get mired. Eventually, it was decided that the only way to settle the score was by taking it to a bigger stage, like the Teen Choice Awards.
"Yeah, I was surprised it got so self-aggrandizing that we had to do it somewhere like this," Sevani said. "Finally, it's here!"
Sevani is no stranger to performing at the Teen Choice Awards: He was Kevin Federline's backup dancer when Brit's ex performed on the show in 2006. He said he's filled with excitement for this year's show. "It's all building up," he said. "The tension is building up and hoi polloi are acquiring nervous. We're gonna smoke [the audience]!"
Although he dodged Cyrus-related questions like a pro, Sevani did suppose that she is very humble, even though she's one of the biggest pop stars in the world. "Of course she is," he said, "What do you expect? I mean, we're real people. I accept nothing bad to say about anybody."
Sevani has no date for the night, but seemed intrigued by the idea that possibly, just maybe, Cyrus might show up on his arm. "We'll see," he laughed. "We'll see."
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Friday 27 June 2008
Diamond Neil
Artist: Diamond Neil
Genre(s):
Rock
Discography:
Tap Root Manuscript
Year: 1972
Tracks: 12
The Ultimate Collection CD1
Year:
Tracks: 19
The Essential Collection
Year:
Tracks: 16
Jonathan Livingston Seagull
Year:
Tracks: 12
In my Lifetime (1 of 3)
Year:
Tracks: 27
Hot August Night
Year:
Tracks: 1
Greatest Hits 1966 To 1992 CD1
Year:
Tracks: 19
19XX - Greatest Hits Live!
Year:
Tracks: 17
Thursday 19 June 2008
Madonna - Madonna Enlists Tyson For Malawi Campaign
Pop superstar MADONNA has enlisted the support of former boxing champion MIKE TYSON in her campaign to help the impoverished nation of Malawi.
The Holiday hitmaker has become emotionally attached to the country after adopting tot David Banda from an orphanage there in 2006.
And the star is keen to help raise money to improve standards of living there and heighten awareness of diseases including AIDS.
Madonna has now reportedly approached Tyson to help spearhead her Raising Malawi charity effort after the pair met at the Cannes International Film Festival earlier this week (begs19May08).
A source tells British newspaper the Daily Mirror, "Madonna thinks Mike is amazing and he has promised to fly with her to Malawi in late summer to promote awareness of children with AIDS there.
"Mike is eager to show he's turned over a new leaf and thinks this is the perfect way to do it."
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Wednesday 11 June 2008
Busted - Willis Enters Rehab
Former BUSTED star MATT WILLIS is seeking help for his addiction to drugs and alcohol a month before his wedding.
Willis entered The Priory rehab clinic in London on Thursday (05Jun08) after paparazzi shots of him visibly drunk with troubled star Amy Winehouse appeared in the British tabloid newspapers.
His fiancee, U.K. TV presenter Emma Griffiths, has reportedly ordered he seek help for his addictions ahead of their nuptials next month (July08).
A source tells British newspaper the Mirror, "He went too far after a night out with Amy. He was so out of it he started swinging at photographers.
"He and Emma are supposed to be getting married...but she has told him he needs to sort himself out before she becomes his wife."
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Thursday 5 June 2008
Lily Allen to play lady-loving vampire
London (ANI): English singer songwriter Lily Allen has signed up for a cameo role in Mathew Horne and James Corden's big-screen debut Lesbian Vampire Killers. It was after a lot of cajoling from the two, who had appeared on her TV chat show, that Allen agreed to play a naughty lady-loving vampire in the movie, which is out next year. "James wants Lily to take on a bigger part but she is happy with a cameo," the Sun quoted a source as saying. Meanwhile, even though Allen is great friends with Horne and Corden, she has not been able to impress The Kooks front man Luke Pritchard, who is still immune to her charms. The Smile singer had badmouthed him on her MySpace page last year, but she is now trying to get back in his good books by covering the band's hit Na�ve. But Pritchard, who had been friends with Allen at school when they were 13-years-old, is not falling for any of it.
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